A type of pediatric brain tumor that may be considered a known genetic pathway for low-grade gliomas is difficult to cure for medical care, according to a new study published in the journal Neuropunch published Thursday. Dr. Fausto Rodriguez, Assistant Professor of Pathology and Oncology at Johns Hopkins University, and colleagues report that the mammalian rapamycin target protein (mTOR) pathway is highly active in low-grade glioma in children , And blocking the use of a pathway for this experiment may reduce the growth of these tumors. We think the function of mTOR can be used as an Achilles heel. Drives the growth of cancer cells, but when mTOR is the co-author Dr. Eric Rabe, a co-author of the study of tumor-suppression-disintegration, an assistant professor at the Johns Hopkins University Kimmel Cancer Center, Pediatrics, Oncology, and Pathology. Although these tumors are considered to be of low grade and are not particularly positive, many patients suffer from severe, life-changing symptoms, so we desperately need better treatment. He added that the impact of brain tumours is the primary cause of cancer-related deaths in more than 4,000 American children each year and not yet 18 years of age. Low-grade gliomas are the most common type of tumor found in the juveniles of the central nervous system and current treatment conditions, including surgery and chemotherapy - a toxic process that often carries serious side effects and explains the team. In addition, many low-grade gliomas are located in areas where they can be easily removed, such as the optic nerve. Removing tumors can lead to loss of vision, and even loss of vision. For example, Loeb also reported that some patients had learning disabilities or after treatment or after tumor resection. As part of their research, Rodriguez and his colleagues organized a sample analysis from 177 pediatric low-grade glioma patients at Johns Hopkins University and other medical facilities. They also used an experiment called MK8669 (ridaforolimus) to block mTOR in a pair of low-grade glioma cell lines in children.
A heat exchanger is a device used to transfer heat, usually to transfer heat from one fluid to another without them mixing. A heat exchanger usually consists of a number of parallel pipes in which one fluid flows through the pipe and another fluid flows through the outside of the pipe. In this way, heat can be transferred from one fluid to another for heating or cooling purposes. Heat exchangers are widely used in many industries, such as chemical, pharmaceutical, food processing, air conditioning and heating systems, etc.
Heat exchanger usually consists of the following components:
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1. Heat exchange pipe: Pipe used to transfer heat, usually made of metal materials, such as copper, stainless steel, etc.
2. Heat exchange surface: A surface used to transfer heat, usually consisting of metal sheets or pipes. The greater the surface area, the higher the heat transfer efficiency.
3. Housing: Housing, usually made of metal or plastic, used to secure heat exchange pipes and surfaces.
4. Seals: Seals used to prevent media leakage, usually made of rubber or silicone rubber.
5. Support: A support used to support a heat exchanger, usually made of steel or cast iron.
6. Import and export pipes: pipes used for medium entry and exit, usually made of metal or plastic.
7. Cleaning hole: A hole used to clean the inside of the heat exchanger, usually located on the upper or side of the heat exchanger.
8. Insulation layer: Insulation layer used to keep the temperature of the heat exchanger stable, usually made of glass wool or polyurethane foam.